Synthesis, determination of stability constants and XRF measurements of Bis 1,2,4-triazole compounds

In this study, two series of new bis 1,2,4-triazoles compounds were synthesized.Fristly, bis triazoles, 4,4 ? -(alkane- ? , ?? -diyl)bis(5-(4-bromobenzyl)-2H-1,2,4-triazol-3(4H)-one) (57, 58, 59, 60, 61, 62 and 63) and 4,4 ? -(alkane- ? , ?? -diyl)bis(5-(4-chlorobenzyl)-2H-1,2,4-triazol-3(4H)-one) (64, 65 and 66), were obtained by the reaction ethyl 2-[(4-bromophenyl) (ethoxy) methylene] and ethyl 2-[(4-chlorophenyl) (ethoxy) methylene] and a seriesof diamine in aqueous media. Then some bis triazoles, diethyl 2,2 ? -(4,4 ? -(alkane- ? , ?? -diyl)bis(3-(4-bromobenzyl)-5-oxo-4,5-dihydro-1,2,4-triazole-4,1-diyl))diacetate (68, 69 and70) and diethyl 2,2 ? -(4,4 ? -(alkane- ? , ?? -diyl)bis(3-(4-chlorobenzyl)-5-oxo-4,5-dihydro-1,2,4-triazole-4,1-diyl))diacetate (71, 72 and 73), were synthesized by the reaction sodium salt of57, 58, 60, 64, 65 and 66 compounds with ethyl bromoacetat.This compounds with some cations were investigated their interaction by using TOCmethod and fluorescence yields for bromine atoms by X-ray fluorescence method.The structures of 16 new compounds synthesized were evaluated by IR, 1H-NMR and13C-NMR spectroscopy. The methods for synthesis were given and possible reaction pathsandmechanisms were discussed.Key Words: Bis 1,2,4-triazole-3-one, Diamine, TOC, EDXRF, Stability Constant.