Biomeolecules sensitive graphene oxide/polyamide based sensor: Preparation and investigation of electrochemical performance

In this study we investigated the selectivity, reliability of a novel, easily prepared and rapid detective electrochemical sensor composed of graphene oxide (GO) and 1,4-phenylenedimethanamine (PDMA) to form graphene oxide supported polyamide p[GO-PDMA] covered on a glassy carbon (GC) electrode for simultaneous determination of uric acid (UA), dopamine (DA) in the presence of ascorbic acid (AA) and dihydroxybenzene isomers; resorcinol (RC), hydroquinone (HQ), catechol (CC). The surface topography and the structure of GC/p[GO-PDMA] were characterized and analyzed in detail by scanning electron microscopy (SEM). Cyclic voltammetry (CV), differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS) were used for voltammetric determination of UA, DA, AA and dihydroxybenzene isomers. Electrochemical analysis results indicate that the GC/p[GO-PDMA] sensor exhibited wide linear ranges with good correlation coefficients and detection limits. Also as real sample electroanalysis, the electrochemical determination of UA, DA in the presence of AA in human serum samples and RC, HQ and CC in tap water were studied.