Development of monolayer mos2 based enzyme sensors

Two-dimensional transition metal dichalcogenide (TMDC) materials have attracted an important deal of interest in electronic, photonic and optoelectronic applications depending on their unique structural properties. Recently, they are also utilized in biosensor applications for different purposes such as diagnosis, detection, sensing of the microorganisms, proteins, gases, etc. In this thesis, the photonic and electronic investigation of the horseradish peroxidase (HRP) enzyme with the interaction of the monolayer MoS2 flakes is studied. Monolayer MoS2 flakes are grown by chemical vapor deposition method with the help of the controllable vacuum system. Optical microscopy, Raman spectroscopy, and atomic force microscopy tools are used for the characterization of the grown MoS2 flakes. After that, for the analysis of the interaction of the enzyme and MoS2 flakes, it is focused on the photoluminescence (PL) and Raman spectrum measurements. The changes on the PL and Raman spectra are observed and interpreted. Followingly, I-V measurements of the interaction between the enzyme and MoS2 flakes are performed and the variations with respect to this interaction are attempted to clarify. We believe that this work can be an executive support for the future studies related to the interactions between TMDC materials and enzyme solutions for the detection, diagnosis, etc.