Helicobacter pylori eradication on dyspeptic symptoms in helicobacter pylori positive patients with dyspepsia symptoms.

Although the literal meaning of dyspepsia is digestive difficulty, it is a term which is used by physicians to examine the different symptoms of epigastric region under a title. H. pylori is the most common gastrointestinal infection in the world. Epidemiological studies points out that, socio-economic conditions are the most important risc factors for H. pylori infection, in general. Several mechanisms are proposed in the etiopathogenesis of dyspepsia but it is controversial which one is more effective. The role of Helicobacter pylori in dyspepsia is a matter for discussion.In this study, we aimed to investigate the effects of Helicobacter pylori eradication on dyspeptic symptoms in Helicobacter pylori positive patients with dyspepsia symptoms.The severity of dyspepsia was determined by applying the modified Glasow Dyspepsia Severity Scoring to the patients who included in the study. Eradication treatment was given to H. pylori positive patients. PPI usage was recommended to H. pylori-negative patients. Patients were invited to our clinic for evaluation of the severity of dyspepsia after the treatment. The severity of dyspepsia was determined after the treatment using the modified Glasow Dyspepsia Severity Scoring.The study performed to 137 patients who match the criteria, complete the treatment and come to control. 75 (54.7%) of patients were female, 62 (45.3%) were male and 62% of patients (85 patients) were found H. pylori positive, 38% (52 patients) were found H. pylori-negative.Compared reduction of post-treatment total score in patients with H. pylori positive and negative which determined by modified Glasow Dyspepsia Severity Scoring, there was no statistically significant difference in both groups (p= 0,667).