Nano-nesnelerin internetinde moleküler haberleşme için pratik alıcı mimarilerinin geliştirilmesi

This thesis aims to bridge the gap between theoretical approaches and practical receiver architectures in the field of Molecular Communication (MC). Within this framework, it focuses on the development of mechanical transduction–based and bio-inspired receiver architectures for the Internet of Nano Things (IoNT) and their integration within the vision of the Internet of Everything (IoE). To this end, an MC receiver based on a Flexure-FET (flexure-sensitive field-effect transistor) biosensor is proposed. By exploiting mechanical transduction, the receiver achieves high-sensitivity detection of both charged and neutral molecules. Building on this capability, the first practical implementation of Weight Shift Keying (WSK) modulation is introduced, in which information is encoded through variations in molecular weight. Analytical modeling and numerical analyses confirm its effectiveness under biologically relevant interference conditions, demonstrating the feasibility of mechanical transduction–based MC. A competitive binding framework is applied to model receptor–ligand interactions and molecular interference, improving both system reliability and molecular selectivity. This framework accounts for multi-ligand dynamics in complex biochemical communication channels. In addition, a cylindrical nanowire array receiver design is proposed, integrating distributed electromechanical coupling and geometrically tunable properties into the MC receiver for enhanced scalability and performance. In the final stage, the MC framework is revisited within an odor-based context. In this approach, odor molecules serve as information carriers, broadening the scope and applicability of MC to more tangible and perceptual domains. Guided by the vision of the Internet of Everything (IoE), this framework establishes a communication bridge that spans from molecular signal detection at the micro/nanoscale to higher-level sensory and cognitive processes, paving the way for the evolution of human-centered and intelligent communication networks. Throughout this thesis, the architectural developments extending from the mechanically transducing receiver to the competitive binding model and the nanowire array design progressively enhance detection sensitivity, reliability, and physical realizability. The integration of the competitive binding framework and the cylindrical nanowire array structure lays the groundwork for future functional receiver architectures in odor-based MC. Overall, the proposed models and architectures provide a foundation for practical, scalable, and biocompatible MC systems, contributing to the advancement of next-generation adaptive and interconnected networks envisioned under the IoE.