Monitoring radiation damping event by inversion recovery and spin echo curves obtained with 400 mhz nmrin h2o-d2o solutions

Novaday high proton magnetizations obtained with high field NMR spectrometers create harmful induction currents in the RF coil. These currents distort the shape of the NMR peaks and complicate the measurement of the relaxation times. This effect is called Radiation damping (RD). Many methods have been developed to eliminate radiation damping effects. However, these methods require the use of both additional electronic hardware and additional computer software. Therefore, it is also important to reduce the radiation damping signal by other means. This study is based on research that tries to reduce the intensity of the water signal by using a high amount of D2O and a small amount of H2O. It was aimed to examine the effects of factors such as increased delay time steps, extended measurement range, consecutive day measurements, increasing the amount of water and adding protein to H2O +D2O solvvent. With this goal, it is also aimed to guide the studies aiming to reduce the signal intensity without using electronic circuits and programs. For this purpose, inversion recovery (IR) curves of the samples containing 0.1 ml H2O + 0.90 ml D2O were found using increasing delay time steps and increasing measurement time intervals.The IR curves of the same solution were also measured in successive days and weeks by choosing different delay time steps and different measurement intervals.By adding albumin to the same solution, IR curves were found for different steps and different measuring ranges.In addition, by increasing the ratio of H2O in the D2O solution, both IR and SE curves were found for different measurement intervals with diferent delay time and SE steps. While the steps used and the measuring range are small, the number of successive recovery magnetizations measured by the IR method is high. In this case, the strength of the recovered magnets is small and the magnetization created by the harmful induction current is dominant. This is why measurements like this show many interpenetrating IR curves. As the measuring range gets larger, the intensity of the recovered magnetizations increases and this increase reduces the effects of harmful magnetization. In such measurements, the number of IR curves decreases towards one and their shape becomes relatively smooth. From the measurements made on the prepared samples on consecutive days, it was revealed that the IR profile did not change, that is, the sample remained unchanged for at least 15 days. It was also observed that increasing the water in the sample deteriorated the IR profile. This is the expected situation. Because the intensity of proton magnetization increases. Adding albumin to the sample has a corrective effect on the IR signal. Because protein increase enlarges the signal via 1/T2 pathway and decreases the signal height. Choosing a narrow measuring range for SE measurements reduces the effects of RD. The reason for this is that the proton magnetizations are less uniform in the small measuring range and the proton signal intensities are high. Echo magnetizations of this intensity play a role in reducing the effects of RD. With this study, it was concluded that parameters such as wide measurement range, large step for waiting times, minimum water ratio in the solution and adding protein to the solution play a role in reducing the effects of RD. In SE measurements, on the other hand, it was concluded that the narrow measurement range reduced the effects of RD.