Synthesis of chiral aminoalcohol based benzimidazoles and investigation of their antimicrobial activities
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Abstract (EN)
New three chiral aminoalcohol-benzimidazole hybrids have been synthesised from commercially available amino alcohols [S(+)-Phenylglycinol, S(-)- Phenylalaninol and S(+)- Leuicinol] and 2-(chloromethyl)-N-tosyl-1-H-benzimidazole. The synthesized compound entirely characterized by IR, NMR, and LC-MS analysis. The antimicrobial properties of compounds 4a, 4b and 4c against important pathogens were investigated by the well-diffusion method. These new chiral compounds have demonstrated significant antimicrobial activity.
Author
İlknur Çiçek
How to Cite
İlknur Çiçek (Master Thesis). Synthesis of chiral aminoalcohol based benzimidazoles and investigation of their antimicrobial activities, 2020, Kırşehir Ahi Evran University.
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