Synthesis of (aryl)(3-substituebenzofuran-2-yl) ketones and their derivatives

In the first step of this study, (3-aminobenzofuran-2-yl)(3-mesityl-3-methylcyclobutyl) ketone compound was synthesized by reaction of 2-chloro-1-(3-mesityl-3-methylcyclobutyl) ethanone compound with 2-hydroxy benzonitrile compound in approprate conditions. (3-aminobenzofuran-2-yl)(3-mesityl-3-methylcyclobutyl) ketone compound's derivates were obtained by being reacted with (3-aminobenzofuran-2-yl)(3-mesityl-3-methylcyclobutyl) ketone compound and chloride compounds. In the second step, the oxime, semicarbazide and thiosemicarbazide derivatives of bis(2-(3-mesityl-3-methylcyclobutan-1-oyl)benzofuran-5-yl)methane compound, which was obtained by being reacted with 2-chloro-1-(3-mesityl-3-methylcyclobutyl)ethanone compound and 5,5'-methylenebisethanone(2-hydroxybenzaldehyde) compound were obtained. The synthesized compounds were characterized by FT-IR, 1H-NMR, 13C-NMR and GC-MS spectroscopic methods.