Integrated simulation and experimental analysis of patient specific abdominal aortic aneurysm

The management and treatment of abdominal aortic aneurysms (AAA) remain a significant challenge in endovascular studies. Recent advancements have emphasized the importance of patient-specific approaches to improve therapeutic outcomes. This research aims to integrate simulation and experimental analysis to enhance the understanding and treatment of AAA in a patient-specific context. An affordable, open source frame work for AAA flow phantom manufacturing is presented. Utilizing a combination of advanced computational simulations and experimental methodologies, this study investigates the biomechanical behavior of AAA. Improvement of flow phantom fidelity using DIC material calibration and verification, physiological pressure levels using Windkessel elements are presented. An improved gear pump design with python based flow phantom control software is discussed. It is shown that an affordable patient specific flow phantom manufacturing framework can be employed and accurately mimic the main hemodynamics of aneurysms. Experimental predictions can be enhanced with fluid structure interaction (FSI) simulation results. The integration of simulation with experimental analysis offers a promising avenue for advancing patient-specific AAA studies. This approach holds potential for improving clinical decision-making and patient outcomes in the management of AAAs, marking a significant step forward in personalized medical treatments.