Effect of lambda cyhalothrin and fenthion pesticides on catalase activity

In this study, effect of lambda cyhalothrin and fenthion pesticides on bovine liver catalase (CAT) activity was investigated. CAT activity was inhibited by increasing lambda cyhalothrin and fenthion pesticides concentrations from 0 ppm to 500 ppm. Under the exposure of 25, 50, 100, 250 and 500 ppm lambda cyhalothrin concentrations, percent of CAT enzyme activity decreases were calculated as 3.4; 11.7; 12.7; 21.2 and 22.5, respectively. Under the exposure of 25, 50, 100, 250 and 500 ppm fenthion concentrations, percent of CAT enzyme activity decreases were calculated as 4.6; 6.2; 6.7; 17.1 and 19.9, respectively. Lambda cyhalothrin inhibited CAT non-competitively and fenthion inhibited CAT competitively.