Kimyasal algılayıcıların tasarımı ve bunların moleküler mantık kapılarındaki uygulamaları

Rational design and synthesis of novel (fluorescent) chemosensors is an active area of supramolecular chemistry. The recognition and signaling moieties are the most important parts in the design of these chemosensors. Despite the numerous studies that were reported in the literature, finding new strategies and mechanisms in the design of fluorescent probes is still of continuing interest. In this thesis, we have proposed some novel and desirable approaches for this purpose. Targeting of medically important anions, such as cyanide and fluoride (chapters 3 and 4), and developing a multianalyte chemosensor for cations (chapter 5) were successfully achieved through a rational design.Moreover, we realized that by the help of fluorescent chemosensors we can address some important solutions, at least to a certain point, to the troublesome issues thatmolecular logic concept faces. Recent research in molecular logic gates produced molecular equivalences of highly complex digital circuits. However, almost all the integration reported in the literature has been ?virtual?, meaning that the output of a unimolecular system is adapted to the output of integrated set of logic gates, such that, the unimolecular system represents the equivalence of a certain complex digital design. Although this approach provides some important advantages, it does not truly solve the concatenation issue at the molecular level. Since physical concatenation of molecular logic gates is important for advanced molecular computing, some novel approaches should be introduced in order to overcome this problem. That is exactly what we are reporting in the chapter 6 of this thesis.Keywords: fluorescence, chemosensors, energy transfer, logic gates,concatenation