Determination of some biocheminal effects of lambda-cyhalothrin active insecticide on Dreissena polymorpha at different temperatures
2022
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Advisor: Prof. Dr. Nuran Cıkcıkoğlu Yıldırım ; Doç. Dr. Osman Serdar
Abstract (EN)
Today, due to the increasing climate change, the effect of temperature, which is considered as the primary indicator of climate change, has become important. In this study, it was aimed to determine the changes in AchE activities, which is an indicator of neurotoxicity, and oxidative stress biomarkers catalase (KAT) and Superoxide Dismutase (SOD) enzyme activities and Glutathione(GSH) and Malondialdehyde (MDA) levels in Dreissena polymorpha exposed to subletal concentrations of Lambda Cyhalotrin at different temperatures for 24 and 96 hours. For this purpose, SOD, KAT, AChE activities and GSH and MDA levels were determined using commercial kits. According to the results obtained; While there was a statistically significant increase in MDA levels due to lambda cyhalothrin administration, a decrease was found in GSH levels. At AChE levels; an overall inhibition was observed. This inhibition is observed especially in the groups administered high-dose lambda-Cyhalothrin. It was also found that the inhibition levels increased depending on the application times.While SOD enzyme activity decreased, KAT enzyme activity increased depending on the application dose. It has been observed that different temperature treatments have different effects on the toxic effects of Lambda-cyhalothrin. It was observed that lambda-cyhalothrin concentrations applied in this study caused oxidative stress and neurotoxicity, and the toxicity of Lambda-cyhalothrin changed depending on the temperature
Author
Dr. Zozan Ketenalp
How to Cite
Zozan Ketenalp (Master Thesis). Determination of some biocheminal effects of lambda-cyhalothrin active insecticide on Dreissena polymorpha at different temperatures, 2022, Munzur University.
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