Synthesis of n-substituted 2-aminothiazoles

In this study, a novel aminothiazole which was not synthesized before reaction of 1,3-dichloroacetone with thiourea was synthesized and its structure was elucidated by FT-IR and 1H, 13C-NMR, single crystal X-ray diffraction methods. New amides were synthesized by reacting the synthesized 4,4'-Disulfanediylbis(methylene)dithiazol-2-amine with benzoylchloride derivatives. A series of compounds containing Amides, disulfide bridge, and imine group, which are also found in the structure of many synthetic or natural drugs, were synthesized and the structures were illuminated by FT-IR and 1H-NMR.