Polimerik membrane uygulamaları için yeni malzemelerin sentezi

The polymeric membranes for antimicrobial applications are in high demand nowadays, since the bacteria had developed the resistance against the antibiotics. The membrane technology could become an efficient tool to cope with the antibiotic resistant bacteria which are becoming an unevitable problem on the health and pocket of a common man. To address this issue, the current research is carried out to synthesize polymer with antibacterial properties. Norbornene and oxonorborne monomers with special modification to achieve antimicrobial properties through N-halamine functional group of hydantoin was synthesized in this thesis. The monomers were polymerized using Ring Opening Metathesis Polymerization (ROMP). The polymer norbornene dicarboximide hydantoin P(NDH) and polymer oxonorbornene dicarboximide hydantoin P(ONDH) were saturated to s-P(NDH) and s-P(ONDH) with p-toluenesulfonyl hydrazide. Polymer s-P(NDH) sucessfuly fabricated into membrane. While s-P(ONDH) could not be fabricated into membranes by itself, the s-P(ONDH) was blended with the polyether sulfone (PES). The s-P(NDH) was also blended with PES, along with PES modified cyanuric acid for comparisons. Hence four membranes were studied, one was pure and three were the blend membranes. The synthesized polymers and the blend membranes were characterized using NMR, IR, DSC, and TG/DTA respectively. The properties of membranes were measured: with SEM, pore sizes were determined: with contact angle measurements, hydrophobocity of surface was determined. Besides, tests for the pure water permeance PWP and BSA protein rejection were conducted. The membranes were studied for their antimicrobial properties against E. coli and S. aureus. The respective membranes were efficient enough to give 100% kill of both bacteria, providing the controlled release of active chlorine and restricted the biofilm formation at the surface of membrane.