Rap-stoermer reaction: Optimization of the synthesis of some substituted benzofurans
2021
0 views
0 downloads
Advisor: Prof. Dr. Murat Koca ; Doç. Dr. Ali Serol Ertürk
Abstract (EN)
The reaction of substituted salicylaldehydes with α-chlorketones to obtain benzofuran-2-yl (alkyl/aryl) ketones, which is a dickman type aldol condensation product in base, solvent and temperature environment, is called the Rap-Stoermer reaction. In this study, Benzofuran-2-yl (Alkyl / aryl) ketones were synthesized by heating substituted salicylaldehydes and α-chlorketones in a base and solvent-free seal (closed cup) environment. Reaction conditions were optimized in terms of yield, time, cost and environment. Characterization of the synthesized compounds was done using spectroscopic methods such as FT-IR, 1H-NMR, 13C-NMR and LC-MS. Key Words: Benzofuran, Solvent Free; One-pot Synthesis; Rap-Stoermer Reaction
Author
Dr. Osman Bozca
How to Cite
Osman Bozca (Master Thesis). Rap-stoermer reaction: Optimization of the synthesis of some substituted benzofurans, 2021, Adıyaman University.
Keywords
License
Tüm Hakları Saklıdır
This work is shared under the specified license terms.
More theses from Adıyaman University
- The assessment of risk factors and sociodemographic characteristics of the children, apply pediatric emergency unit with febrile convulsion complaint and hospitalized in our clinic(2018)
- Evaluation of traditional total prosthesis, implant supported overdenture and "all-on-four" system applied to atrophic mandible wi̇th bilateral temporomandibular joint prosthesis using finite element analysis method(2025)
- Purin-pyrimidin fluctations of FMF disease (Familial Mediterranean Fever) and DNA(2010)
- Some classes of difference fuzzy numbers defined by an Orlicz function(2010)
- With the method of Van der Waals, ground state and excited states of the magic numbers(2010)
- Soft sets and some soft algebraic structures(2011)