Comparison of human heart-type fatty acid- binding protein with cTNI, CK-MB, and myoglobin and the detection of their roles in the early detection of acute myocardial infarction

The aim from this study is to accurately measure the concentration of H-FABP, Troponin T, CK, cTnI, CK-MB and myoglobin. We aimed to evaluate the accuracy of H-FABP in a point-of-care setting for early detection of myocardial damage (or ruling out AMI) in patients presenting to the emergency department with chest pain or dyspnoea. In this study, 100 subjects with varying degrees of disease activity and a control group consisting of 55 healthy individuals. There were divided into two groups; group A: 100 patients with standard test results confirming MI and group B: 55 without MI confirmed by standard test results. There was a clear importance of age, as the study showed injuries at early ages. The rest of the chemical parameters showed clinically significant and significant differences through which we concluded that patients with improved MI showed higher sensitivity and specificity for myoglobin and h-FABP but lower sensitivity and specificity for CK-MB and cTnI. This means that we can use myoglobin and h-FABP tests as good indicators for detecting MI.