The studies on antimicrobial activites of three species from the family lamiaceae (Prunella vulgaris, Thymus longicaulis Subsp. longicaulis and Teucrium chamaedrys Subsp. chamaedrys) distributed in düzce region

ABSTRACT The studies on Antimicrobial Activites of Three Species from the family Lamiaceae (Prunella vulgaris, Thymus longicaulis subsp. longicaulis and Teucrium chamaedrys subsp. chamaedrys) Distributed in Düzce region. Kaan Çetin Düzce University Graduate School of Natural and Applied Sciences, Department of Biology Master's Thesis Supervisor: Prof. Dr. Başaran DÜLGER July 2022, 100 pages In this study, ethanol, chloroform and ethyl acetate extracts obtained from Prunella vulgaris L., Thymus longicaulis subsp. longicaulis C.Presl. and Teucrium chamaedrys subsp. chamaedrys L. (Lamiaceae) collected from Düzce province were investigated for their antimicrobial activities against the bacterial cultures; Pseudomonas aeruginosa, Escherichia coli, Salmonella typhimurium, Streptococcus pyogenes, Proteus vulgaris, Klebsiella pneumoniae, Staphylococcus aureus, Enterococcus faecalis, Bacillus cereus, Bacillus subtilis and the yeast cultures; Candida albicans, Candida tropicalis, Kluyveromyces marxianus, Cryptococcus neoformans, Debaryomyces hansenii by disc-diffusion method. The highest antibacterial activity of Prunella vulgaris L. was measured against P. aeruginosa (14 mm) bacterium in the ethanol extract. Besides, the highest antifungal activity of the plant was determined in the ethanol extract against the yeast culture as K. marxianus (15 mm). While the highest antibacterial activity of Thymus longicaulis subsp. longicaulis C.Presl. plant was measured against B. subtilis (15 mm) bacterium in the ethanol extract, the highest antifungal activity was found against the yeast culture C. neoformans (12 mm) in the ethanol extract. Likewise, the highest antibacterial activity of Teucrium chamaedrys subsp. chamaedrys L. plant was detected against S. aureus (14 mm) bacterium while the highest antifungal effect was determined in K. marxianus (17 mm) as the yeast cultures in the ethanol extracts of the plant. In addition to all these, chemical characterization of the ethanol extracts of three plant species used in this study was investigated and evaluated by Gas Chromatography Mass Spectroscopy (GC/MS) technique. Keywords: Antimicrobial activity, Lamiaceae, Gas Chromatography Mass Spectroscopy (GC/MS)