Medical SpecialtyOpen Access

Factors affecting parametrial involvement in stage 1a2 -1b1 cervical cancer patients and selection of low risk patients

2013
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Advisor: Prof. Dr. Ali Ayhan

Abstract (EN)

Objective:The aim of the study is to identfy early stage (1A2-1B1) low risk (tumour size ≤ 2 cm,stromal invasion ≤50 %,and LVSİ negative) cervical cancer patients and to evaluate parametrial involvement and the role of less radical surgery(cone,simple trachelectomy,simple hysterectomy) Material and Methods:We evaluated cervical cancer patients operated in Baskent University Ankara Hospital at Gynecologic Oncology Division between the years 2007-2013.We identified 168 patients as stage 1A2 and 1B1.13 patients was stage 1A2 (7.7 %) and 155 patients was stage 1B1 (92.3 %).Mean age was 49.5(range ,29 -80).Histologies were ;132 patients (78.6 %) squamous cell,23 patients (13.7 %) adenocancer,13 patients (7.7 %) adenosquamous cancer respectively.Mean follow-up time was 73 months(range ,3-75 months).139(82.7 %) patients was performed Radical hysterectomy+BSO+BPPLND,14 patients (8.2 %) was performed Radical hysterectomy+USO+BPPLND,7 patients (4.2 %) was performed radical trachelectomy +BPPLND,4 patients (2.4 %) was performed parametrectomy+upper 1/3 vagenectomy+BPPLND and 2 patients(1.2 %) was performed Conization +BPPLND .Statistical analyses are done by using SPSS 17. Results:We identified 26 patients with early stage ,low risk factors and there was no parametrial involvement,lymph node metastases ,recurrance and death of disease in these patients.And these results was similar with retrospective studies in litarature.Conservative surgical approach is hopefull in low risk-early stage cervical cancer patients and the results of ongoing prospective randomised studies are waiting for safety and feasibility of conservative management in these patients.

Author

Dr. Hüseyin Akıllı

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Hüseyin Akıllı (Medical Specialty Thesis). Factors affecting parametrial involvement in stage 1a2 -1b1 cervical cancer patients and selection of low risk patients, 2013, Baskent University.

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