Evaluation of seropozitivity, seroconversion and transmition ratio to fetus of toxoplasma gondii and cytomegalovirüs during pregnancy

11.SUMMARYAim:We aimed to evaluate the Toxoplasma Gondiiand HCMV seroconversion in each trimester of the pregnancyand seropozitivity ratio in maternal blood and cord blood.Methods: Pregnant women in the first trimesterattempted to Inonu University Obstetrics Clinic and pregnantwomen in the third trimester of pregnancy attempted to theemergency room from April, 2004 to October, 2005 wererecruited. Blood samples were drawn from 153 pregnantwomen at every trimester and from 159 pregnant women attheir 3. trimester of pregnancy for serological testing. 217pregnant women were taken for HCMV enfection at samecondition.Toxoplasma gondii specific IgM and IgG wereanalyzed by Enzyme-linked Immunosorbent Assay(ELISA)and Indirect Fluorescent Antibody Test (IFAT). Cordblood samples were collected immediately after delivery andToxoplasma gondii specific IgM and IgG were evaluated withthe same serological tests. HCMV specific IgM and IgG wereanalyzed by Enzyme-linked Immunosorbent Assay(ELISA).Statistical calculations was made by SPSS forWindows 11?0