Evaluation of hepatic hemodymanic changes in cholestatic patient by color doppler ultrasound

This study is aimed to determination of frontier findings warning physisians related to hemodymanic changes having development possibility in liver resulted from cholestasis by using such a method of color Doppler ultrasonography (RDUS) which is non invasive and reliable.In this context; 42 patient groups having high hepatic enzyme level, 41 patient groups having high hepatic enzyme level and bilurubin, and 24 control groups constituted from healthy persons are examined with RDUS. In all cases congetion index (CI), fibrosis index (FI), hepatic vasculer index (HVI), hepatic artery resistive index (HA-RI), hepatic artery pulsatility index (HA-PI), portal vein velocity (PVH), portal vein diameter (PVÇ) and spleen size are evaluated. According to these parameters, statistical difference among the control group, patient group of high hepatic enzyme level, and cholestasis patient group are evaluated.According to the FI, HVI, HA-PI parameters, between the patient group of high hepatic enzyme level and control group are determined significant difference (p<0,05). On the other hand, according to the CI, HA-RI, PV diameter, and spleen size parameters, these groups are not observed any significant difference (p>0,05).Between the patient group of high hepatic enzyme level and the cholestasis patient group, and between the control group and the cholestasis patient group are obtained significant difference as statistical in all parameters (p<0,05).According to the CI, FI, HA-RI, HA-PI, PVH, and HVI parameters, these groups are determined high statistical significant difference (p<0,001). While CI, FI, HA-RI, HA-PI, PVÇ, and spleen size have increased in the cholestasis patient group; in turn, PVH and HVI have decreased.The results of our study show that RDUS have a utility and reliable modality on the changes happened in hepatic hemodynamy that might appeared by presence of biliary cirrhosis and its progression developed in the cholestatic patients