Master'sOpen Access

The biotransformation of pregnenolone by some Aspergillus species

2010
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Advisor: Yrd. Doç. Dr. Kudret Yıldırım

Abstract (EN)

In this work, pregnenolone was incubated with Aspergillus terreus MRC 200365 and Aspergillus tamarii MRC 72400 in order to see how it would be metabolized by these two fungi. Incubation with both Aspergillus terreus MRC 200365 and Aspergillus tamarii MRC 72400 afforded two metabolites.The structures of the metabolites were elucidated by the melting points, 1H NMR, 13C NMR and IR spectra. Each incubation afforded 3ß-hydroxy-17a-oxa-D-homo-androst-5-en-17-one and 17a-oxa-D-homo-androst-5-en-3,17-dione.

Author

Dr. Emine Yasemin Gülcüoğlu

How to Cite

Emine Yasemin Gülcüoğlu (Master Thesis). The biotransformation of pregnenolone by some Aspergillus species, 2010, Sakarya University.

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