Application of Pd(II) catalyzed heck coupling reaction in supercritical carbon dioxide (ScCO2) and organic solvent

In this thesis, new phosphine type ligands that containing phosphorus and nitrogen donor atoms (2-(bis(3,5-dimethylphenyl)phosphino)benzylidene)-4-(heptadecafluoro octyl)aniline (L1) and (2-(bis(3,5-trifluoromethylphenyl)phosphino)benzylidene)-4-(heptadecafluorooctyl)aniline (L2) have been synthesized. The synthesized ligands and Pd(II) complexes were fully characterized by FT-IR, 1H, 13C, 31P, 19F NMR and HRMS techniques. The catalytic activities of the Pd (II) complexes were investigated in Heck coupling reactions which carried out in both ScCO2 and organic solvent. For this purpose, firstly the solubilities of Pd (II) complexes in ScCO2 were investigated. After, test reactions which on the model reaction between bromobenzene and styrene, were carried out for two different solvents. Furthermore, these iminophosphine-Pd(II) complexes were successfully applied as catalysts and high catalytic activities were obtained for Heck cross coupling reactions of activated (4-bromonitrobenzene) and deactivated (4-bromotoluene) aryl bromides with styrene.