Development of a mock circulation loop for use in artificial blood vessels' tests

Mock Circulation Loop (MCL) refers to devices commonly used to simulate artificial vascular systems and similar biomechanical processes. Current MCL systems pose challenges for researchers due to their high costs and limited accessibility. These systems are also mechanically and electronically complex. On the other hand, new research projects in artificial vessels and related fields are emerging every day, and there is an increasing need for MCL systems that are affordable, easy to access, and capable of reducing experimental costs. Although a low-cost MCL machine may not meet all experimental needs, it can provide researchers with a practical tool for conducting trial-and-error processes during the initial phases of their studies. Furthermore, it is essential to provide students and new researchers in this field with opportunities to gain hands-on and real-world experimental experience on an affordable platform, thereby enhancing the quality of their education. In this thesis, a mock circulation loop with low cost, adequate measurement capabilities, easy production, and reproducibility has been designed and manufactured. Four main objectives have been set within the scope of this study: (I) to establish the MCL using simple and low-cost production methods, (II) to simulate natural vascular expansion on the MCL using a typical artificial vessel model, (III) to generate a typical arterial pressure waveform through precise control of the pump, (IV) to demonstrate the ability of the integrated sensors to measure flow and pressure differences caused by vessel expansion. This thesis aims to develop a platform that facilitates research processes and contributes to the education of the next generation of researchers.