Effect of pertubation on pregnancy rates before IUI treatment in unexplained infertile patients

In this prospective randomized study, patients diagnosed with unexplainedinfertility underwent pertubation prior a controlled ovarian stimulation and intrauterine insemination protocol. The effects of pertubation on their successive pregancy rates were evaluated. A total of 180 patients were included in the study, and amongst these pertubation of the uterine cavity was carried out in 79 patients before insemination. One patient in the pertubation group was later excluded since insemination could not be done due to reasons in follow up. There were no significant differences between the demographic characteristics of both the study and control groups. When the pregnancy rates of both groups were evaluated, 14 patients (%17. 8) in the study group achieved pregancy. Three patients (3. 8%) had a biochemical pregnancy, 1 (1. 3%)patient miscarried and 10 patients (12. 7%) had live births. In the control group, a total of 24 pregnancies (23. 8%) were achieved, amongst which one patient had a biochemical pregnancy (1%), 3 (3%) miscarried and 20 (19.8%) resulted in live births. There was no significant difference between both groups? total pregnancy rates and live birth rates (p>0.05). When the rate of pregnancy loss was investigated, a loss of 21% in total was discovered. There was no significant difference between the control and study groups when pregnancy loss rates were considered (p>0.05).We conclude that, this study on a homogenous group of unexplained infertile patients, the addition of pertubation to a COH+IUI treatment protocol does not affect pregnancy rates.Key words: Unexplained infertility, pertubation, gonadotrophin