Prognostic effect of serum sodium, glucose, creatinine in patients with acute pulmonary thromboembolism

Pulmonary embolism is a disease with high morbidity and mortality. Predicting prognosis in acute PTE RVD, troponin positivity and PESI are used. In our study in each center can be reached easily serum sodium, creatinine and glucose levels studied prognostic values and correlation between currently used markers. In our study, 112 patients were evaluated retrospectively who has been hospitalized in Chest Disease Clinic of Akdeniz University Hospital between January 2010 - December 2012, ventilation / perfusion scintigraphy with a high probability of PTE or acute PTE in chest CT angiography without chronic renal failure, and diabetes mellitus. Demographic characteristics, vital signs, mental status, PESI, derived from the first admission, especially glucose, sodium and creatinine levels, including routine biochemical tests, D-dimer, troponin levels, echocardiographic results were analyzed. Of the total 112 PTE cases, 86 (76.8%) were staying stable in the first 30 days (group 1), 26 (23.2%) died within the first 30 days (group 2) were determined. 27.6% of patients hyponatremia was detected and mortality rates in the first 30 days were significantly higher than in patients with normal serum sodium concentration (respectively, 70.9%, 4.4%, p = 0.001). On the first admission serum sodium level under the 135 mmol / l approximately 48-fold increase in the risk of death is determined. In our study, patients who died within 30 days of average eGFR 45.5 mL/dk, the 100.3 mL/dk the patients who were stable. eGFR < 60 milliliter / min and ? 60 milliliter / min compared to the prognosis of the two group, eGFR <60 milliliter / min with 41.67-fold increase in mortality compared to the other group (p <0.001). The average values of the patients at admission serum glucose 129.1 mg/dl fatal group average value was 140 mg/dL, and significantly higher than stable patient group (p < 0.001). Troponin-positive, RVD identified, PESI class V patients have a high mortality rate and in these patients presence of low serum sodium levels and eGFR, high levels of serum glucose, that supports these new three markers have high prognostic values. Diagnostic performance the highest marker of the presence of low serum sodium level. If there is a combination of three parameter, mortality risk 100%. Serum sodium, glucose and creatinine levels can be used separately or together, suggest that the prediction of prognosis in acute PTE