Electrochemical sensor development for ascorbic acid (vitamin C) and uri̇c acid of determination based poly(glioksalbis (2-hydroxyaniline))

In this study, a novel polymer film of poly(glyoxalbis(2-hydroxyanil), P(GBHA), was prepared by electropolymerization of glyoxalbis(2-hydroxyanil) (GBHA) on a glassy carbon electrode (GCE) and this electrode was utilized to the simultaneous detection of the ascorbic acid (AA) and uric acid (UA). The electrochemical synthesis parameters effecting the formation of P(GBHA) films were investigated and the optimum synthesis conditions were determined. Scanning electron microscopy (SEM), cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and attenuated total reflection Fourier Transform infrared spectroscopy (FT-IR) methods were employed for the characterization of the P(GBHA) film prepared under the optimum conditions. The electrochemical sensör was exhibited fairly electrocatalytic activity towards the oxidation of AA and UA. The linear response ranges for the determination of AA and UA were 1,0-2000 and 1,0-200 µmol L−1 with the detection limit of 0,26 and 0,3 µmol L−1, respectively. These results present that the P(GBHA) is a promising substance for the production of electrochemical sensors with highly sensitivity. Keywords: Electrochemical sensor, poly(glyoxal-bis(2-hydroxyanil), ascorbic acid, uric acid, voltammetric detection