The antagonistic and synergistic investigation of the antimicrobial characteristics of extracts of some herbs

This study was aimed to compare the antimicrobial features of the extracts of Achillea millefolium L., Anthemis cretica L. Cichorium intybus L., Euphorbia seguieriana Necker, Hypericum perforatum L. which were generated by using different solutes (methanol, diethyl ether) antagonistically and synergistically. Plant extracts were generated by using the Soxhlet Method. In the antimicrobial activity studies of the extracts, Escherichia coli, Acinetobacter baumannii, Salmonella typhimurium were used as Gram negative bacterias; Staphylococcus aureus, Bacillus cereus, Listeria monocytogenes were used as the Gram positive bacterias. The antimicribial activities of the extracts were determined microbroth dilituon method. According to the results of the research; All plant extracts obtained using both methanol and diethyl ether solvent were determined to be more effective against Gram positive bacteria. While the whole plant extract showed the most effect on Bacillus cereus bacteria, Hypericum perforatum L. methanol extract was the most effective plant against Gram positive bacteria. Achillea millefolium L.: Cichorium intybus L., Achillea millefolium L.: Hypericum perforatum L. and Cichorium intybus L.: Hypericum perforatum L. methanol mixture extracts and Achillea millefolium L.: Hypericum perforatum L. diethyl ether extract showed a synergistic effect, while other plant mixture extracts showed semi-synergistic or ineffective properties.