Long term outcome of laparoscopic nissen rossetti fundoplication for the treatment of gastroesophageal reflux disease

Aim: The aim of this thesis is to evaluate the long term outcome of the laparoscopic Nissen Rossetti fundoplication for the treatment of gastroesophageal reflux disease in terms of the relief of symptoms, quality of life and prevention of pathologic acid reflux. Material and Method: Thirty two patients who underwent laparoscopic Nissen Rossetti fundoplication for the treatment of gastroesophageal reflux disease between the dates of January 2003 and June 2006 were included in this thesis. The long term outcome was assessed by subjectively comparing the preoperative and postoperative symptoms and Gastroesophageal reflux-Health related quality of life index. As an objective assessment of the pathological reflux, patients underwent 24 hour pH monitorization in the preoperative and postoperative period. Results: The median postoperative follow-up period for the patients was 28 ± 7.92 (16-52) months. A significant increase was observed in the quality of life scores in the postoperative period when compared to the preoperative period (p = 0.001) and the DeMeester scores decreased significantly (p = 0.001). The postoperative dysphasia was observed even in the long term in most of the patients, without having an important effect on the quality of life. Conclusions: In the treatment of gastroesophageal reflux disease, laparoscopic Nissen Rossetti fundoplication is an effective and successful method in achieving the desired outcome such as preventing pathological reflux, relieving the symptoms and improving the quality of life in the long term.