Evaluation of the effects of PRF, CGF and AFG application on wound healing following gingivectomy and gingivoplasty operations

Evaluation of the effects of PRF, CGF and AFG application on wound healing following gingivectomy and gingivoplasty operations Aim: The aim of this study was to evaluate the effect of PRF, CGF and AFG application on early wound healing after gingivectomy and gingivoplasty operations. Material and Method: In the study designed split mouth, gingivectomy and gingivoplasty surgery were performed on 19 patients. The postoperative PRF, CGF, and AFG applied areas were compared with the control regions. 0th,7 th,14 th and 28 th on the days, the surgical area was painted with mira-2-tone solution and evaluated in the ImageJ program. Wound healing was evaluated with H2O2 test, VAS-Pain, and LTH index on 7th, 14th and 28th days. The patients were asked to evaluate their aesthetic perceptions on the VAS aesthetic scale. Results: The amount of staining with mira-2 tone on the 7th and 14th days of the control group was found to be significantly higher than the test groups, there was no difference between the test groups. LTH index values of the control group on the 7th, 14th and 28th days were found to be significantly lower than the test groups. There was no significant difference between the groups in the epithelization assessment performed with the H2O2 test. It was observed that the use of thrombocyte concentrate on the 7th day reduced postoperative early pain. Patients were highly satisfied with postoperative aesthetics. Conclusion: After gingivectomy and gingivoplasty operations, PRF, CGF and AFG application were found to have positive effects on wound healing. However, it was observed that PRF, CGF and AFG applications were not superior to each other in terms of secondary wound healing. Keywords: Autologous fibrin glue, concentrated growth factor, gingivectomy, gingivoplasty, platelet rich fibrin.