The investigation of risk factors in patients with hospitalized candidiuria

The prevalence of Candida infections increases all over the world due to increased use of immunosuppressive drugs and antibiotics, more often application of invasive procedures. Urinary tract infections (UTI) are the most common infections in hospitalized patients. Although the bacteries are the most common agents of UTI, fungal agents are isolated from % 10 of all cases and Candida species are most common in these cases. This study is aimed to determine the risk factors of candiduria in hospitalized patients. This study included the patients above 18 years old people who had positive urine cultures for Candida spp. between August 2012- August 2013. We recorded the general risk factors, physical examination findings, biochemical and microbiological laboratory results for each patient. Candida species which are isolated from the patient identified with Phoenix yeast ID automatize system and antifungal sensitivity tested with integral system yeast plus kit. The study included 90 patients; the study group 45 patients who had candiduria, and control group 45 patient who had bacteriuria. Among investigated risk factors, DM (p=0.057), urinary catheter usage (p=0.015), invasive procedure performed in last 30 days (p=0.024), long term hospitalization (p=0.017), antibiotic usage (p=0.001), history of intensive care unite (ICU) admition (p=0.058) were found more frequent in study group then the control group. The most frequent isolated Candida species was C.albicans. Among isolated C. albicans; %4.5 of them was resistant fluconazole, %4.8 of them was resistant amphotericine B, %9.5 of them was resistant variconazole. No resistance was found to flusitozin. In result of the this study; controlled use of antibiotics, performing urinary catheterization with appropriate indications, regulation of blood sugar in diabetic patients and the shortest appropriate period of hospitalization are thought to be effective in reducing frequency of candidiuria.