Factors affecting patient and graft survival in renal transplant patient in the Karadeniz Technical University Faculty of Medicine

İntroduction and Aim: Chronic Kidney disease is worldwide seen and an important public health problem. Patients with end stage kidney disease could survive with renal replacement therapy. Among the renal replacement therapies, the best treatment modality is kidney transplantation (KT). KT has been performed successfully since march 2009 in Karadeniz Technical University (KTU). In our study, we aimed to determine the factors that affect graft survival and patient survival in kidney transplant patients in KTU Faculty of Medicine. Material and Methods: 42 patients over 18 years old who performed a kidney transplant in KTU Faculty of Medicine between March 2009 and November 2015 were included into our study. Kidney transplant recipient and donor demographics, posttransplant follow-up, treatment regimens were analyzed retrospectively. Statistical analysis of the data was performed using SPSS 13.0 for Windows statistical software package. Results: 13 (%31) of KT patients were living related and 29 (%69) of than were cadaveric KT. According to the Kaplan-Meier analysis 1st and 5th year graft survival in living related KT was %100 and %100 respectively while 1st and 5th year graft survival of cadaveric KT were found to be %90 and %78 respectively. Patient survival of living related KT were found to be %92 at 1st and 5th years while patient survival of cadaveric KT were %86 and at 1st and 5th years. Delayed graft function and posttransplant erythrocyte transfusion were found to be statistically significant between KT patient with graft loss and KT patient with functional graft. Advanced recipient and donor age, history of coronary artery disease, post transplant erythrocyte transfusion, and high kidney donor profile index (KDPI) were found to be statistically significant between dead and alive KT patients. Conclusion: In our study, the factors affecting graft and patient survival in our center (KTU school of Medicine) were evaluated. Dead censored graft failure were found to be affected by posttransplant erythrocyte transfusion and delayed graft function while advanced recipient and donor age, history of coronary artery disease, posttransplant erythrocyte transfusion and high scores in KDPI were found to affect the patient survival.