Investigation of the dimensional change of magnetite (Fe3O4) magnetic nanomaterials depending on working conditions

The biomedical applications of magnetic nanomaterials (MNPs) have been explored for more than 30 years. MNPs have been used in various areas such as in medicine, drug targeting systems, hyperthermia, biosensors, magnetic cell separation and contrast agents in magnetic resonance imaging (MRI). Especially in the use of in-body MNP, magnetic materials are desired to be small in size. These materials increase in size when coating or drug binding. The smaller the MNP is produced, the higher the possibility of in-body use after coating. This study has been carried out to examine the size change of MNPs depending on the working conditions. The size change of the magnetic nanomaterials to be obtained by the co-precipitation method has been monitored by changing the conditions such as pH, temperature, stirring speed and the type of base used. In addition, these dimension changes will change the thermal properties, mechanical properties, optical properties, electrical properties and magnetic properties of magnetic nanomaterials. New features will create new application areas. Thanks to these changes, it has been determined under which conditions the magnetic nanomaterial with the best properties and the smallest size is formed. In the characterization tests of the samples obtained using different working conditions; it has been checked whether the MNPs synthesized by XRD were magnetite (Fe3O4). FESEM allows to observe the morphology of the iron oxide core and to estimate its true diameter. In the SEM analysis, whether the MNPs are spherical or not and the diameters of the MNP nuclei are measured. Pre-size examination of MNPs has been characterized by dynamic light scattering (DLS), which measures the hydrodynamic diameter of dispersed nanoparticles. In the VSM analysis, the magnetic behavior of the MNPs has been determined by looking at the change of the magnetization obtained at room temperature with the magnetic field. The surface charge, which has an effect on the repulsion and pull values between the particles, has been characterized by the zeta (ζ) potential analysis