The impacts of clinical, laboratory and pathological findings on the succes of sperm retrieval in patients with non-obstructive azoospermia

The study aims to evaluate the correlation of TESE and histopathology with various features of NOA cases who consulted to our university-based infertility clinic, and the probability of prompting couples about TESE success and to investigate the cost reduction chance through cost-beneficial aspects. 125 patients were enrolled in this study.The ratio of NOA was 15.07%. Sperm recovery rate was 40%. Sperm recovery in> 30 year-old group decreased slightly. Cases with unprotected intercourse>10 years, resulted similary.. Well-known negative FSH-testis volumes correlation lacked when the patient had additional diseases and/or genitourinary surgery . FSH and LH levels were significantly different between TESE positive and negative groups ( p=0.006, p=0.001 respectively). Sperm recovery rate was 5.6% when FSH levels were 20-30 mIU/ml. Success rate in bilateral TESE group was 14.2%; 96% of TESE negative patients had bilateral TESE. Histopathology subgroups differantiated significantly in the means of FSH, LH and testis volume values.To conclude, no parameters here predicted succesful TESE outcome. However, in prior bilateral TESE, increased FSH and deletion of AZFa/AZFb conditions; patients may learn about failure rates and possible disease inheritance. This may reduce procedure costs. Poor prognosis determination, may help the rearrangement of the appropriation of infertility in health policies.