The role of serum and seminal plasma magnesium levels in premature ejaculation

THE ROLE OF SERUM AND SEM NAL PLASMA MAGNES UM LEVELS NPREMATURE EJACULAT ONDr.Taner TanınmışINTRODUCTION-AIM: Premature ejaculation (PE) is the most frequent male sexualfunctional disorder. There is no consencus about the etiopathogenesis.In this study, serum and seminal magnesium levels were detected in patients who admittedto urology outpatient with PE and in control group. Index of Premature Ejaculation was filledout to both group and scorred to evaluate and degree the sexual dissatisfaction, the deficiencyof ejaculation control and the areas of distress caused by PE. Our aim is to search the place ofthis form in the evaluation of the subjective complains of the patients with PE.Finally, the comparison of patients with PE and the control group about the demographic,sociocultural and sexual life characteristics is also aimed.MATERIAL-METHOD: Detailed medical and sexual history is taken from the controlgroup and from 35 patients who have admitted to Adnan Menderes University Department ofUrology with the complain of premature ejaculation which compliance the DSM IV criteria.Abdominal, genital system and rectal examination, anal tonus and bulbocavernosus reflexevaluation were performed. Among both group, NIH/KPSI, IIEF, IPSS forms and a surveyabout ?Index of Premature Ejaculation? and the reasons effecting sexual function were filledout. Also, subjective and for twice chronometric intravaginal ejaculation latent time (IELT)were recorded. Simultaneously, serum and semen samples were obtained. All the results wereevaluated statistically.RESULTS: Among the patients who were evaluated between December 2006-June 2007,the mean age and the rate of education below high school were detected higher in the groupwith PE.There was no statistically significance in semen magnesium levels (PE 13,66 ± 12,76mg/dL, control group 20,52 ± 19,62 mg/dL) and in serum magnesium levels (2,56 ± 0,37mg/dL vs 2,54 ± 0,26 mg/dL) among both groups. No significant relation was found in serummagnesium levels and IELT measurements.Total IPSS and score of life quality were significantly higher in PE group. Among thisgroup, in the evaluation of NIH/KPSI scores urinary symptoms were significantly increasedand quality of life got worse. Total IIEF and IIEF-6 scores were signicantly decreased in PEgroup.When the answers of the PE patients to areas of sexual satisfaction, ejaculation controland distress in Index of Premature Ejaculation were scored, significant increase was observedin all areas.Significantly, negative relation was detected between mean IELT and ejaculation controlarea in Index of Premature Ejaculation. Also, in this group, statistically significant relationwas found between sexual satisfiaction area and ejaculation control area.CONCLUSION: No statistically significance was detected in serum and semenmagnesium levels and no significant relation was found between serum magnesium levelsand IELT measurements in patients with PE. To reach definite results, further investigationshave to be performed.In patients with PE, IPSS and NIH/KPSI scores were increased, total IIEF and IIIEF-6scores were decreased and the quality of life got worse. In the evaluation and treatment ofpatients with PE, low urinary tract symptoms, presence of chronic prostatitis and erectiledisfunction have to be considered.Index of Premature Ejaculation can be used in patients with PE to evaluate and to degreethe subjective complains.In the approach of PE, evaluation of the partners can be useful and demographic,sociocultural and sexual life characteristics can provide important information.