Comparison of left ventricular hypertrophy and diurnal blood pressure pattern in end stage renal failure patients on continuous ambulatory peritoneal dialysis and automated peritoneal dialysis
2012
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Danışman: Prof. Dr. Yasemin Erten
Özet (EN)
Comparision of left ventricular hypertrophy and diurnal blood pressure pattern in end stage renal disease patients on automated peritoneal dialysis and continuous ambulatory peritoneal dialysis.Since cardiovascular disease is the main cause of mortality in majority of dialysis patients, blood pressure control and evaluation of cardiac functions have great importance in these patients. Peritoneal dialysis (PD) has some theoretical advantages over hemodialysis, however, several studies have shown increased cardiovascular risk in PD patients after loss of residual renal function (RRF). Hypertension (HT) with non-dipper blood pressure pattern is also related with increased risk of LVH in end stage renal disease (ESRD) patients. Automated peritoneal dialysis (APD) is increasingly used in patients with ESRD. There are limited studies comparing blood pressure pattern, RRF and LVH in continuous ambulatory peritoneal dialysis (CAPD) and APD patientsIn this study we aimed to investigate the effect of different peritoneal dialysis regimens on blood pressure control, diurnal blood pressure pattern, and LVH in PD patients.Results of our study;?There was no significant difference about gender, body mass index, use of erythropoietin and vitamin D, levels of calcium and phosphate, duration of dialysis, Kt/v frequency of LVH and RRF values between the two groups.?However, mean age was significantly lower in APD compared to CAPD patients.?Ambulatory mean systolic, diastolic and mean arterial blood pressures (daytime, nighttime and 24 hour) were higher in the APD group, but this difference was statistically insignificant.?There was no difference non-dipper blood pressure rate between the two groups.?There were also no significant differences in systolic and diastolic blood pressure loads and left ventricular mass index (LVMI) between the two groups.?However, LVMI was correlated with systolic, diastolic and mean arterial blood pressure levels (mean daytime and nighttime 24 hour measurements)?Positive correlation was observed between LVMI and systolic and diastolic blood pressure loads (daytime and nighttime values)?There was a significant relationship between LVMI and diastolic non-dipper pattern.?Left ventricular mass index was negatively correlated with RRF and hemoglobin (Hb) levels?Residual renal function was found to be positively correlated with Hb levels.?İn multivariate logistic regression analysis models, there was a significant relation between LVMI and RRF in all 3 models. Also there was a positive relation between LVMI and systolic, diastolic and mean blood pressureIn this study, we found no difference in blood pressure levels, diurnal blood pressure pattern and LVH between APD and CAPD patients. According to our results, control of blood pressure and preservation of RRF are more important
Yazar
Nuh Ataş
Bu Yayına Nasıl Atıf Yapılır
Nuh Ataş (Medical Specialty Thesis). Comparison of left ventricular hypertrophy and diurnal blood pressure pattern in end stage renal failure patients on continuous ambulatory peritoneal dialysis and automated peritoneal dialysis, 2012, Gazi University.
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