The relationship between plasma atherogenic index (PAI) and CHA2DS2-VASc scores in st-elevation and non-ST myocardial i̇nfarcti̇ons

Aim: In this study, the relationship between the CHA₂ Dec-VASc score, Plasma atherogenic index (PAI), monocyte HDL ratio (MHR), platelet lymphocyte ratio (PLR) and neutrophil lymphocyte ratios of patients admitted to the emergency department and diagnosed with myocardial infarction was evaluated. It was also aimed to determine the correlations with ST elevation (STEMI) and Non-ST Myocardial Infarctions (NSTEMI). Method: This study was conducted on patients diagnosed with myocardial infarction in the Emergency Department of Kırşehir Education and Research Hospital between 2020-2023 and is a retrospective descriptive speciality thesis research. 200 STEMI, 200 NSTEMI patients and 200 control group healthy volunteers were included in this study. Symptoms: The average age of the whole patients included in the study and the control group was 60.70±12.33. When scores and blood values were compared according to the groups, significant differences were found in CAD VASC, PAI, PLR, NLR and MHR score values. CAD VASC score is higher in the NSTEMI group compared to STEMI and control group. PAI score was higher in both NSTEMI and STEMI groups compared to the control group. MHR is higher in the STEMI group than in the control group. NLR is higher in both NSTEMI and STEMI groups compared to the control group. It was found that there is a weak correlation between CAD VASC score and NLR and PLR in a positive direction. It was found out that there is a weak correlation between PAI and MHR in the positive direction, and a weak correlation between PLR and Dec. A one-unit increase in CADVASC score increases MI risk by 1.60 times, a one-unit increase in PAI score increases it by 3.24 times, a one-unit increase in NLR increases it by 2.59 times, while a one-unit increase in PLR reduces MI risk by 1.013 times. Conclusion: According to the data obtained from this study, all inflammation parameters, which are indicators of atherosclerosis, were found to be increased in patients with myocardial infarction. No significant correlation was found between CHA₂DS₂-VASc and PAI, but CHA₂DS₂-VASc score was found to be significantly higher especially in NSTEMI and PAI in both MI groups. In this respect, while the predictive effect of CHA₂DS₂-VASc score is high in clinics and emergency departments, especially for NSTEMI, the predictive effect of PAI for a certain subgroup of myocardial infarction is not significant. More comprehensive and multicentre studies are needed to more clearly evaluate the usibility of these two parameters in myocardial infarction risk scoring. Keywords: myocardıal ınfarctıon, stemı, nstemı, cha₂ds₂-vasc, paı, nlr