Optimization and study on mass trasnfer parameters of extraction of flavan-3-ol compounds from grape seed

In this study, effects of temperature, particle size and liquid-solid ratio on extraction of phenolic compounds in grape seed (Vitis vifinera L.) were investigated and extraction conditions were optimized using response surface methodology (RSM). Effective diffusion coefficient (De) of phenolic compounds in seed and mass transfer coefficient (KL) were calculated from analytical solution of Fick?s second law.The highest yields were found as 15.5 % for total extract, 4.80 % for total phenolic compounds (TPC) and 2.60 % for total polymeric procyanidin (TPP) at extraction conditions of 0.220 mm, 42.5 ºC and liquid-solid ratio 15. While effective diffusion coefficients, De, were range from 0.67x10-11 to 6.22x10-11 m2s-1, mass transfer coefficients, KL, were between 0.89x10-5 and 3.62x10-5 ms-1.