Synthesis, characterization and biological activites of new schiff base metal complexis

In this study, the treatment of 4-aminoantipyridine (1) and 2-pyridinecarboxaldehyde (2) yielded the formation of 4- (2-Pyridylmethylene) amino-1-phenyl-2,3-dimethyl-5-pyrazolone (3) which was reduced to 1,5-dimethyl-2-phenyl-4- (pyridin-2-yl-methylamino) -1H-pyrazol-3 (2H) –one (4). Nickel and cobalt complexes from compound 4 were synthesized. The antioxidant activity of synthesized complexes was investigated using DPPH• free radical scavenging, ABTS•+ radical cation scavenging and reducing power assays. It was observed that nickel complex revealed more activity than that of the cobalt complex.