Researching the levels of chemerin in childhood obesity

Childhood obesity is a state that is supposed to diagnose and treat early because it reveals many chronic process like diabetes, hypertension and atherosclerotic heart disease. With the increasing incidence during recent years childhood obesity becomes a public health concern. Adipokines accuse for chronic process that comes with obesity like type II diabetes, non-alcholic fatty liver disease and hypertension. Increasing number of adipokines along with discovering new molecules include chemerin. There are numerously animal and human study about chmerin and obesity. Role of chemerin is still not understood due to different results of these studies. This study was done in order to research chemerin levels and its relation with complications of childhood obesity.Study was performed in March-August 2011 with 60 obese and 30 health children at 7-16 years old. Cases which had acute or chronic infection, chronic or syndromic disease and edogenous obesity, excluded from study. Fasting glucose, AST, ALT and chemerin levels evaluated by blood samples that was taken from all cases; in addition to these insulin, total cholesterol, HDL cholesterol, LDL cholesterol, triglyseride levels evaluated by bllod samples from obese cases. Serum chemerin level determined 229,72±69,90 ng/ml in obese cases and was higher than controls. But there was no relationship between chemerin and insuin resistance, non-alcholic fatty liver disease, hypertension, dyslipidemia. In conclusion increased number of cases are necessary in order to investigate the relationship between chemerin and obesity complications.