Determination of physical and mechanical parameters of biocompatible gelatine films

The main aim of this thesis is to determine appropriate mechanical strength of biocompatible solutions and films and physical parameters respect to medical applications. Gelatin was chosen as a based biocompatible material. Various concentrations of gelatin were determined such as 5%, 3.3%, 2% ,1.42%, 1% and 0.6%. Films were prepared using these solutions. Viscosity measurement were done for solutions and tensile test were done for films and results of each experiments were analysed to obtain mechanical results for each material. After analysing results of experiments two concentrations of pure gelatin solution 5% which was most concentrated and 2% which had convenient results were chosen to observe influence of riboflavin, glucose and NaCl. Concentration of glucose and NaCl were altered between 1% to 5% at a rate of 1% increment. Films were prepared using these solutions. Viscosity measurement and tensile test were performed for each concentration too. Besides the glucose and NaCl riboflavin was added to pure gelatin concentration to observe affect of riboflavin which is UV sensitive material. The viscosity values and flow behaviour of each solution and Elasticity Modulus of each film were determined after experimental procedure. Viscosity and flow behavior of solutions were related with mechanical properties of fluid form and Elasticit Modulus was related with mechanical properies of solid form of each sample. These parameters were used in order to determine which material is appropriate for biomedical application.