The effect of COVID-19 on HBA1C and fasting blood sugarlevels in diabetic patients

Introduction: Corona virus (Covid-19) (Severe Acute Air Syndrome) type II (SARS-2) emerged in 2019 and has spread all over the world. There are studies reporting that the virus negatively affects vital functions in diabetic patients. The fact that the virus directly affects β-cells and causes metabolic disorders may cause a more severe course of the disease in diabetics. Objective: This study was conducted to examine the effect of Corona virus on HBA1C and fasting blood glucose levels in diabetic patients. Method: This study was conducted in a quarantine hospital in Ramadi, Iraq, between February 1, 2022 and August 1, 2022. 130 people, 54 women and 54 men, were included in the study. 22 people from the study groups constitute the non-diabetic control group. 108 people consist of patients who have been diagnosed with diabetes before and who have positive Covid-19 test. Fasting blood glucose levels were measured on Day 1 (GLU1) before starting Covid-19 treatment and on Day 2 and 3 (GLU2 and GLU3) after treatment. In addition, HbA1c levels were examined before starting the treatment (HbA1c 1) and 2 times (HbA1c 2 and HbA1c 3) with an interval of 2 months after starting the treatment. ix Bulgular: When we compared the GLU and HbA1c levels of Group 2, Group 3 and Group 4 with the Control group (CONT) (GROUP 1), it was determined that both GLU and HbA1c levels were high (p<0.02, p<0.03, respectively). GLU 1, GLU 2, GLU 3 and HbA1c 1, HbA1c 2, HbA1c 3 levels of Group 2 were 214.63 ± 100.28, 166.58 ± 50.70, 134.10 ± 35.51 and 10.10 ± 0.21, 8.30 ± 0.29, respectively. , was determined to be 6.80 ± 0.31 and there was a decrease in GLU 2, GLU 3 and HbA1c 2, HbA1c 3 measured after treatment. GLU 1, GLU 2, GLU 3 and HbA1c 1, HbA1c 2, HbA1c 3 levels in Group 3 were determined as 175.80 ± 60.38, 215.10 ± 95.73, 268.40 ± 135.51 and 7.60 ± 0.33, 9.60 ± 0.23, 12.20 ± 0.21, respectively. It was observed that the patients in this group had an increase in the levels of GLU 2, GLU 3 and HbA1c 2, and HbA1c 3 measured after the treatment. GLU 1, GLU 2, GLU 3 and HbA1c 1, HbA1c 2, HbA1c 3 levels in group 4 were determined as 179.0 ± 62.18, 238.10 ± 115.43, 192.0 ± 86.91 and 7.90 ± 0.31, 10.70 ± 0.20, 8.70 ± 0.31, respectively. It was observed that the levels of GLU 2, GLU 3 and HbA1c 2, HbA1c 3 measured after treatment in group 4 patients were higher and not constant compared to before treatment. Sonuç: According to the results of our study, it was observed that 28 of 108 diabetic patients (Group 2) responded to the treatment and had a decrease in blood glucose levels. It was determined that 28 of the patients (Group 3) had an increase in blood glucose levels despite the treatment. It was observed that blood glucose levels of 52 patients (Group 4) were high and irregular. These results show us that the blood glucose levels may increase more after Covid-19 in the vast majority of diabetic patients.