Characterization of hydrogels synthesized for use in eczema treatment

In this study, to determine the most suitable formulation for use in eczema treatment hydrogels containing HEMA, Eudragit L-100 and fusidic acid in different compositions were synthesized by confinement method using ammonium persulfate (APS) chemical initiator and ethylene glycol dimethacrylate (EGDMA) cross-linker. Fusidic acid confined p(HEMA-co-Eudragit-co-fusidic acid) in the synthesis of the hydrogel used Taguchi method and determined the optimum synthesis conditions. These hydrogels were calculated % swelling activity in different pH environments and water. Fourier Transform Infrared Spectroscopy (FT-IR) and Scanning Electron Microscopy (SEM) analyzes were performed to characterize these hydrogels. Also; creams formulations developed and contained in chitosan and HEMA based polymers have been synthesized. Fourier Transform Infrared Spectroscopy (FT-IR) and Scanning Electron Microscopy (SEM) analyzes were performed to characterize these cream formulations. In addition, the stability of the formulations to 28 days; the changes in parameters such as appearance, centrifugation, pH, relative density, viscosity, spreading were investigated.