Study of the possible relations between seminal plasma antisperm antibodies and thyroid function tests in men infertility

Infertility is defined as a man in a reproductive age who cannot conceive despite having regular unprotected intercourse for one year. It accounts for 40-50% of infertility in humans. In this study, the patients were gathered in 4 groups: 1. group - Prednisolone group, 2. group - Levothyroxine group, 3. group - control group٫ 4. group - Levothyron and Prednisolone group. In group 1, the drug taken in patients who only received prednisolone and undergone ovulation induction had no significant effect on Anti-T and Anti-TPO. Biochemically, conceiving rate was 16% higher in this group. In group 2, patients were diagnosed with thyroid disease and were taking levothyroxine for a long time, and they continued to take the drug during ovulation induction. The patients in group 3 (control group) did not take any medication except ovulation induction. Significant decrease was observed in Anti and Anti-TPO values in goup 4 (P = 0.037 and P = 0.015, respectively). The combined use of both drugs significantly decreased the biochemical pregnancy rates in this group. In this thesis study, we aimed to examine various parameters that define and process in this type of infertility and to determine the presence of possible relationships between antibodies and thyroid function tests.