Evaluation angiotensin converting enzyme (Ace), interleukin-6, urea, creatinine, lactate dehydrogenase (Ldh) and other parameters in patients with COVID-19

Angiotensin (Ang) II pathway plays important regulatory effects on both the hemostasis of the circulatory system and the immunological responses. This pathway plays a significant part in the pathophysiology that underlies both acute lung damage and acute respiratory distress syndrome. The purpose of this study included: determining ACE and interleukin-6 and other parameters in patients with Covid-19. The purpose of this research was to analyze the relationship between illness severity and ACE activity, as well as to evaluate the level of ACE activity present in COVID-19 by comparing them to healthy persons. It is essential to the effective care of COVID-19 patients that risk factors for early development toward severe illness and/or death be identified. In this study, 90 subjects (45 women and 45 men) with varying degrees of disease activity and a control group consisting of 90 healthy individuals matched for age, gender and body mass index will be evaluate (ACE), IL-6, urea, creatinine, lactate dehydrogenase and other parameters in patients with covid-19). The study found clinical significance age, weight and body mass(P<0.05). They were also of great importance to ACE and LDH(P<0.05), and their impact was evident in Covid 19 patients. While there was no clear importance for fats. The study concluded that the factors of age, weight, ACE and LDH have the greatest role in the development and severity of Covid-19 disease.