The synthesis of heterocyclic substituted bisbenzimidazole derivatives and investigation of their properties

This thesis consist of three parts. In the first part; work with piperidine,morpholine, pyrrolidine, benzimidazole and bisbenzimidazoles done by previousresearchers in considered.In the second part, the synthesis methods of the newly synthesised heterocylicsubstituted bisbenzimidazoles derivatives were given. The newly synthesisedcompounds in this work are shown in scheme 1.The last part contains 1H -NMR, 13C-{1H}-NMR, FT-IR, micro analysis(elemental analysis), melting points data of the compounds. The discussion of theresults obtained have been made in this part.Key Words : Piperidine, Morpholine, Pyrrolidine, Benzimidazoles derivatives, Bis-benzimidazole derivatives, Heterocyclic compoundsN N NNBr-(CH2)3-Br R-X2Cl++NN NNR R1 R= 2-piperidiniumethyl chloride2 R= 2-morpholiniumethyl chlorideHN N NNNBr-(CH2)4-Br R-X + + 2ClNNNNNRR3 R= 2-piperidiniumethyl chloride4 R= 2-morpholiniumethyl chloride5 R= 2-pyrrolidiniumethyl chlorideNNN NBrCH2CH=CHCH2Br R-X2Cl+ +NN NNR R6 R= 2-piperidiniumethyl chloride7 R= 2-morpholiniumethyl chloride8 R= 2-pyrrolidiniumethyl chlorideScheme 1 : Synthesised bisbenzimidazole compounds and their derivatives