Indications for medical treatment and treatment efficiency of tubal ectopic pregnancy in our clinic

Objective: Effectiveness of treatment was surveyed in patients who were diagnosed as tubal ectopic pregnancy and received single dose methotrexate treatment. Materials and Methods: 70 patients who received single dose methotrexate treatment due to tubal ectopic pregnancy were included. All of the patients were hemodynamically stabile. Demographic characteristic of patients, β-hCG values, transvaginal ultrasonographic findings and factors that effect the success of the treatment were researched. Results: Datum of totally 70 cases were analysed. 47 cases (%67.14) were successfully treated, in 23 cases (%32.86) treatment was unsuccessful. Age avarage of the cases was 30,14±5,63. In 45 of the cases (%64.28), single dose methotrexate ; in 25 of them (%35.71) second dose methotrexate was applied. 31 (%68.8) of 45 patients who received single dose was succesfully treated and 16 (%64) of 25 patients who received the second dose were successfully treated. In 8 of 14 patients who received single methotrexate that result failed and applied laparoscopiy salpengectomy; 6 of them was applied laparotomy with salpengectomy.In 3 of 9 patients who received the second dose methotrexate that result failed and applied laparoscopy salpengectomy, and 6 of them were applied laparotomy with salpengectomy. The β-hCG resolution time of single dose methotrexate group and second dose methotrexate group was 22,54±7,63 days and 29,76±9,59 days, respectively, which was statistically significant (p=0,003). Conclusion: Methotrexate treatment is effective and safe option for treatment of tubal ectopic pregnanies. Especially single dose methotrexate treatment have high successful rates and it provides easily practise. Keywords: Tubal ectopic pregnancy, methotrexate