Investigation of the electrophilic amination of organometal reagents with acetone O-(4-chlorophenysulfonyl)oxime

The three methods were developed for electrophilic amination reaction with organometals using acetone O-(4-chlorophenylsulfonyl)oxime (1). The best results in obtaining the corresponding aryl amines were obtained under room temperature conditions, with yields ranging from 52-83 % with organomagnesium (bromomagnesium organocyanocyanocuprate and dibromomagnesium diorganocyanocuprate) and 40-78 % with organomagnesiums (copper-catalyzed). In the light of the data obtained, it was observed that the stoichiometric efficacy of organomagnesiums was more effective than copper-catalyzed organomagnesiums in the synthesis of arylamines functionalized by electrophilic amination, the copper-catalyzed organomagnesiums were more effective in terms of reaction time. Among the organocuprates, it was observed that high-order organocuprates got more successful results than low-order organocuprates.