Research into comparative investigation of Pelargonium endlicherianum fenzl. (Geraniaceae) root extracts with Umca® preparation

In this study antioxidant and antibacterial activities of the root extracts of Pelargonium endlicherianum Fenzl. growing in Turkey, were investigated by comparing with the drug Umca®, which is prepared from Pelargonium sidoides DC. roots.Extracts with different polarities were prepared via maceration of P. endlicherianum roots, collected from Dağküplü village of Eskişehir, using 11% Ethanol and 70% Methanol as solvent. The antioxidant activity of the extracts and Umca® were investigated by measuring total phenol level, assigning reducing power, 1,1-diphenil-2-picrylhydrazyl (DPPH?) free radical-scavenging and ß-carotene/linoleic acid oxidation inhibiting power. All the experiments were repeated three times. Antioxidant activity of the 70% methanol extract was found to be higher than that of Umca®.Antibacterial activity of the root extracts and Umca® against Gram negative and Gram positive microorganisms were investigated by the microdilution technique. 70% methanolic extract displayed similar activity with the reference against Serratia marcescens.Antioxidant and antibacterial activities of P. endlicherianum roots are shown for the first time.