The role serume HSP 70 levels at diagnosis of patients with ST eleveted myocart infarction

ABSTRACTTHE ROLE SERUME HSP70 LEVELS AT DIAGNOSIS OF PATIENTS WITH ST ELEVETED MYOCART INFARCTIONAcute myocardial infarction with ST elevation (STEMI) is the leading cause of morbidity and mortality all over the world in the first place; despite efforts to take all the protection, it becomes a serious health problem with increased frequency. Therefore, early diagnosis and risk assessment issues about STEMI is of great importance.We study, the relationship between the level of HSP70 and cardiac markırs. We aimed to determine the disease process within HSP70 changes levels who admitted to our emergency department with STEMI.Our prospective study presented who were admitted to Firat University Medical School Hospital Emergency Department with the ECG derivation at least 0.1 mV ST segment elevation in 2 consecutive derivation. Fifty patients were included above 40 years of age and control group consisted of 50 people who have no underlying comorbid disease. Blood samples were collected for measurement of serum HSP70 and cardiac markır levels in the patients at admission, and 3 days later blood samples were collected to the patients The findings level analyzed statistically.In our study, HSP70 were found to be significantly higher in the third day patients than the level of incidence (761.433-575.905 pg / ml) (p <0.05). HSP70 levels were also higher than control group patients at admission (575.905-381.544), but found no statistically significant (p>0.05).We found that 3rd day patients with STEMI seeing a high levels of HSP70 in follow-up study. ACS has previously been correlated with HSP70, similar results were obtained. We believe that more research needs to be done on this subject.Keywords: Acute coronary syndrome, STEMI, HSP70.