Study the effect of parameter Cu-Zn, D-dimer and superoxid dismutase in patients with pulmonaray disaeases‏‏

Lung disease is defined by increased airway responsiveness to environmental stimuli and reversible airflow restriction as a long-term inflammatory condition of the lungs. Using serum to measure antioxidant enzyme activity and erythrocytes (packed cells) to separate and purify the Cu-Zn superoxide dismutase enzyme, the researchers studied 50 lung patients treated with inhaled salbutamol and another 50 healthy people. This is what we found out in our study: It has been found that individuals who use inhaled salbutamol had a significant drop (P <0.001) in total antioxidant capacity (TAC) and Cu-Zn superoxide dismutase activity in their serum, according to the study. Significant decreases in SOD activity and TAC were seen in the sera of pulmonary patients, as well as significant differences in the levels of Zn, Cu, and D-dimer in the sera of the patients compared to the healthy group (P <0.001). Sera of pulmonary patients who utilised inhaled salbutamol showed a substantial (p<0.001) drop in (Copper and selenium concentration) and a significant (p>0.05) increase of (Zinc concentration). Keywords: Cu-Zn, Superoxide dismutase, D-Dimer, Pulmonary diseases